Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3

Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3

Abstract Background TRIP13 is highly expressed in several cancers and is closely connected with cancer progression. However, its roles on the growth and metastasis of hepatocellular carcinoma (HCC), and the underlying mechanism are still unclear. Methods Combining bioinformatics with previous studie...

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Bibliographic Details
Main Authors: Jianning Yao, Xuexiu Zhang, Jiaheng Li, Dongyao Zhao, Bing Gao, Haining Zhou, Shilin Gao, Lianfeng Zhang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Cancer Cell International
Subjects:
Bioinformatics
TRIP13
HCC
Metastasis
TGF-β1/smad3
Online Access:http://link.springer.com/article/10.1186/s12935-018-0704-y

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