Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
Cancer cells adapt to the changing microenvironment by activating different pathways through multiple mechanisms. Here the authors identify long noncoding RNAMIR31HGas a HIF-1α co-activator required for the induction of the hypoxic response and show its oncogenic role in oral carcinogenesis.
Bibliographic Details
| Main Authors: |
Jing-Wen Shih,
Wei-Fan Chiang,
Alexander T. H. Wu,
Ming-Heng Wu,
Ling-Yu Wang,
Yen-Ling Yu,
Yu-Wen Hung,
Wen-Chang Wang,
Cheng-Ying Chu,
Chiu-Lien Hung,
Chun A. Changou,
Yun Yen,
Hsing-Jien Kung |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2017-06-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms15874
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