Activation of lymphocyte cytolytic machinery: where we are?

Activation of lymphocyte cytolytic machinery: where we are?

Target cell recognition by cytotoxic lymphocytes implies the simultaneous engagement and clustering of adhesion and activating receptors followed by the activation of an array of signal transduction pathways. The cytotoxic immune synapse represents the highly specialised dynamic interface formed bet...

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Bibliographic Details
Main Authors: Ricciarda eGalandrini, Cristina eCapuano, Angela eSantoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Immunology
Subjects:
Signal Transduction
Cytotoxicity
CTL
NK cell
cytolytic synapse
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00390/full

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