Enzymatic synthesis and chemical inversion provide both enantiomers of bioactive epoxydocosapentaenoic acids
Epoxy PUFAs are endogenous cytochrome P450 (P450) metabolites of dietary PUFAs. Although these metabolites exert numerous biological effects, attempts to study their complex biology have been hampered by difficulty in obtaining the epoxides as pure regioisomers and enantiomers. To remedy this, we sy...
Main Authors: | Maris A. Cinelli, Jun Yang, Amy Scharmen, Joey Woodman, Lalitha M. Karchalla, Kin Sing Stephen Lee |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-11-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520309238 |
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