High Oct4 expression: implications in the pathogenesis of neuroblastic tumours

Abstract Background Neuroblastic tumours (NBTs) are paediatric solid tumours derived from embryonic neural crest cells which harbour their own cancer stem cells (CSC). There is evidence indicating that CSC may be responsible for tumour progression, chemotherapy resistance and recurrence in NBTs. Oct...

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Bibliographic Details
Main Authors: Ezequiel Monferrer, Rebeca Burgos-Panadero, Maite Blanquer-Maceiras, Adela Cañete, Samuel Navarro, Rosa Noguera
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-5219-3