Amiloride-enhanced gene transfection of octa-arginine functionalized calcium phosphate nanoparticles.

Amiloride-enhanced gene transfection of octa-arginine functionalized calcium phosphate nanoparticles.

Nanoparticles represent promising gene delivery systems in biomedicine to facilitate prolonged gene expression with low toxicity compared to viral vectors. Specifically, nanoparticles of calcium phosphate (nCaP), the main inorganic component of human bone, exhibit high biocompatibility and good biod...

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Bibliographic Details
Main Authors: Juan Ramón Vanegas Sáenz, Taichi Tenkumo, Yuya Kamano, Hiroshi Egusa, Keiichi Sasaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5690608?pdf=render

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