MD Simulations of tRNA and Aminoacyl-tRNA Synthetases: Dynamics, Folding, Binding, and Allostery

MD Simulations of tRNA and Aminoacyl-tRNA Synthetases: Dynamics, Folding, Binding, and Allostery

While tRNA and aminoacyl-tRNA synthetases are classes of biomolecules that have been extensively studied for decades, the finer details of how they carry out their fundamental biological functions in protein synthesis remain a challenge. Recent molecular dynamics (MD) simulations are verifying exper...

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Bibliographic Details
Main Authors: Rongzhong Li, Lindsay M. Macnamara, Jessica D. Leuchter, Rebecca W. Alexander, Samuel S. Cho
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:International Journal of Molecular Sciences
Subjects:
coarse-grained
atomistic
empirical force field
catalytic mechanism
editing
Online Access:http://www.mdpi.com/1422-0067/16/7/15872

Internet

http://www.mdpi.com/1422-0067/16/7/15872

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