Minimising Blood Stream Infection: Developing New Materials for Intravascular Catheters

Catheter related blood stream infection is an ever present hazard for those patients requiring venous access and particularly for those requiring long term medication. The implementation of more rigorous care bundles and greater adherence to aseptic techniques have yielded substantial reductions in...

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Main Authors:	Charnete Casimero, Todd Ruddock, Catherine Hegarty, Robert Barber, Amy Devine, James Davis
Format:	Article
Language:	English
Published:	MDPI AG 2020-08-01
Series:	Medicines
Subjects:	intravascular catheter CRBSI biofilm CVC antimicrobial antifouling
Online Access:	https://www.mdpi.com/2305-6320/7/9/49

id	doaj-ffa180e88d054112b4b93ce31e79129e
record_format	Article
spelling	doaj-ffa180e88d054112b4b93ce31e79129e2020-11-25T03:41:10ZengMDPI AGMedicines2305-63202020-08-017494910.3390/medicines7090049Minimising Blood Stream Infection: Developing New Materials for Intravascular CathetersCharnete Casimero0Todd Ruddock1Catherine Hegarty2Robert Barber3Amy Devine4James Davis5School of Engineering, Ulster University, Jordanstown BT37 0QB, Northern Ireland, UKSchool of Engineering, Ulster University, Jordanstown BT37 0QB, Northern Ireland, UKSchool of Engineering, Ulster University, Jordanstown BT37 0QB, Northern Ireland, UKSchool of Engineering, Ulster University, Jordanstown BT37 0QB, Northern Ireland, UKSchool of Engineering, Ulster University, Jordanstown BT37 0QB, Northern Ireland, UKSchool of Engineering, Ulster University, Jordanstown BT37 0QB, Northern Ireland, UKCatheter related blood stream infection is an ever present hazard for those patients requiring venous access and particularly for those requiring long term medication. The implementation of more rigorous care bundles and greater adherence to aseptic techniques have yielded substantial reductions in infection rates but the latter is still far from acceptable and continues to place a heavy burden on patients and healthcare providers. While advances in engineering design and the arrival of functional materials hold considerable promise for the development of a new generation of catheters, many challenges remain. The aim of this review is to identify the issues that presently impact catheter performance and provide a critical evaluation of the design considerations that are emerging in the pursuit of these new catheter systems.https://www.mdpi.com/2305-6320/7/9/49intravascular catheterCRBSIbiofilmCVCantimicrobialantifouling
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Charnete Casimero Todd Ruddock Catherine Hegarty Robert Barber Amy Devine James Davis
spellingShingle	Charnete Casimero Todd Ruddock Catherine Hegarty Robert Barber Amy Devine James Davis Minimising Blood Stream Infection: Developing New Materials for Intravascular Catheters Medicines intravascular catheter CRBSI biofilm CVC antimicrobial antifouling
author_facet	Charnete Casimero Todd Ruddock Catherine Hegarty Robert Barber Amy Devine James Davis
author_sort	Charnete Casimero
title	Minimising Blood Stream Infection: Developing New Materials for Intravascular Catheters
title_short	Minimising Blood Stream Infection: Developing New Materials for Intravascular Catheters
title_full	Minimising Blood Stream Infection: Developing New Materials for Intravascular Catheters
title_fullStr	Minimising Blood Stream Infection: Developing New Materials for Intravascular Catheters
title_full_unstemmed	Minimising Blood Stream Infection: Developing New Materials for Intravascular Catheters
title_sort	minimising blood stream infection: developing new materials for intravascular catheters
publisher	MDPI AG
series	Medicines
issn	2305-6320
publishDate	2020-08-01
description	Catheter related blood stream infection is an ever present hazard for those patients requiring venous access and particularly for those requiring long term medication. The implementation of more rigorous care bundles and greater adherence to aseptic techniques have yielded substantial reductions in infection rates but the latter is still far from acceptable and continues to place a heavy burden on patients and healthcare providers. While advances in engineering design and the arrival of functional materials hold considerable promise for the development of a new generation of catheters, many challenges remain. The aim of this review is to identify the issues that presently impact catheter performance and provide a critical evaluation of the design considerations that are emerging in the pursuit of these new catheter systems.
topic	intravascular catheter CRBSI biofilm CVC antimicrobial antifouling
url	https://www.mdpi.com/2305-6320/7/9/49
work_keys_str_mv	AT charnetecasimero minimisingbloodstreaminfectiondevelopingnewmaterialsforintravascularcatheters AT toddruddock minimisingbloodstreaminfectiondevelopingnewmaterialsforintravascularcatheters AT catherinehegarty minimisingbloodstreaminfectiondevelopingnewmaterialsforintravascularcatheters AT robertbarber minimisingbloodstreaminfectiondevelopingnewmaterialsforintravascularcatheters AT amydevine minimisingbloodstreaminfectiondevelopingnewmaterialsforintravascularcatheters AT jamesdavis minimisingbloodstreaminfectiondevelopingnewmaterialsforintravascularcatheters
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Minimising Blood Stream Infection: Developing New Materials for Intravascular Catheters

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