Ubiquitin-specific peptidase 18 regulates the differentiation and function of Treg cells

Ubiquitin-specific peptidase 18 regulates the differentiation and function of Treg cells

Ubiquitin-specific peptidase 18 (USP18) plays an important role in the development of CD11b+ dendritic cells (DCs) and Th17 cells, however, its role in the differentiation of other T cell subsets, especially in regulatory T (Treg) cells, is unknown. In our study, we used Usp18 KO mice to study the l...

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Bibliographic Details
Main Authors: Lu Yang, Yukai Jing, Danqing Kang, Panpan Jiang, Na Li, Xinrong Zhou, Yan Chen, Lisa S. Westerberg, Chaohong Liu
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Genes and Diseases
Subjects:
CD25
Foxp3
ICOS
Regulator T cell
USP18
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300465

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