DNA Double Strand Break Repair Pathways in Response to Different Types of Ionizing Radiation

DNA Double Strand Break Repair Pathways in Response to Different Types of Ionizing Radiation

The superior dose distribution of particle radiation compared to photon radiation makes it a promising therapy for the treatment of tumors. However, the cellular responses to particle therapy and especially the DNA damage response (DDR) is not well characterized. Compared to photons, particles are t...

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Bibliographic Details
Main Authors: Gerarda van de Kamp, Tim Heemskerk, Roland Kanaar, Jeroen Essers
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
linear energy transfer
double strand break repair
combination therapy
DNA repair pathway
end resection
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.738230/full

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