Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective
Molecular testing has acquired a relevant role for diagnostic and prognostic stratification of indeterminate thyroid nodules. Besides the available commercial solutions marketed in the United States, various local testing strategies have been developed in the last decade. In this setting, the modern...
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Online Access: | https://www.mdpi.com/2673-5261/2/3/20 |
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doaj-ffacc5d5e5924307bd42a856cec149872021-09-26T00:30:02ZengMDPI AGJournal of Molecular Pathology2673-52612021-07-0122023324010.3390/jmp2030020Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist PerspectiveClaudio Bellevicine0Roberta Sgariglia1Mariantonia Nacchio2Caterina De Luca3Pasquale Pisapia4Francesco Pepe5Giancarlo Troncone6Department of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyMolecular testing has acquired a relevant role for diagnostic and prognostic stratification of indeterminate thyroid nodules. Besides the available commercial solutions marketed in the United States, various local testing strategies have been developed in the last decade. In this setting, the modern <i>interventional cytopathologist</i>, the physician who performs the both aspirate and the morphologic interpretation plays a key role in the correct handling of fine-needle aspiration (FNA) samples not only for microscopy but also for molecular techniques. This review summarizes experiences with local approaches to the molecular testing of thyroid FNA, highlighting the role of the modern interventional cytopathologist.https://www.mdpi.com/2673-5261/2/3/20interventional cytopathologistFNAthyroidmolecular techniquesmolecular pathologyNGS |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Claudio Bellevicine Roberta Sgariglia Mariantonia Nacchio Caterina De Luca Pasquale Pisapia Francesco Pepe Giancarlo Troncone |
spellingShingle |
Claudio Bellevicine Roberta Sgariglia Mariantonia Nacchio Caterina De Luca Pasquale Pisapia Francesco Pepe Giancarlo Troncone Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective Journal of Molecular Pathology interventional cytopathologist FNA thyroid molecular techniques molecular pathology NGS |
author_facet |
Claudio Bellevicine Roberta Sgariglia Mariantonia Nacchio Caterina De Luca Pasquale Pisapia Francesco Pepe Giancarlo Troncone |
author_sort |
Claudio Bellevicine |
title |
Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective |
title_short |
Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective |
title_full |
Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective |
title_fullStr |
Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective |
title_full_unstemmed |
Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective |
title_sort |
molecular testing of thyroid fine-needle aspiration: local issues and solutions. an interventional cytopathologist perspective |
publisher |
MDPI AG |
series |
Journal of Molecular Pathology |
issn |
2673-5261 |
publishDate |
2021-07-01 |
description |
Molecular testing has acquired a relevant role for diagnostic and prognostic stratification of indeterminate thyroid nodules. Besides the available commercial solutions marketed in the United States, various local testing strategies have been developed in the last decade. In this setting, the modern <i>interventional cytopathologist</i>, the physician who performs the both aspirate and the morphologic interpretation plays a key role in the correct handling of fine-needle aspiration (FNA) samples not only for microscopy but also for molecular techniques. This review summarizes experiences with local approaches to the molecular testing of thyroid FNA, highlighting the role of the modern interventional cytopathologist. |
topic |
interventional cytopathologist FNA thyroid molecular techniques molecular pathology NGS |
url |
https://www.mdpi.com/2673-5261/2/3/20 |
work_keys_str_mv |
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