Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective

Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective

Molecular testing has acquired a relevant role for diagnostic and prognostic stratification of indeterminate thyroid nodules. Besides the available commercial solutions marketed in the United States, various local testing strategies have been developed in the last decade. In this setting, the modern...

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Main Authors: Claudio Bellevicine, Roberta Sgariglia, Mariantonia Nacchio, Caterina De Luca, Pasquale Pisapia, Francesco Pepe, Giancarlo Troncone
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Molecular Pathology
Subjects:
interventional cytopathologist
FNA
thyroid
molecular techniques
molecular pathology
NGS
Online Access:https://www.mdpi.com/2673-5261/2/3/20
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spelling doaj-ffacc5d5e5924307bd42a856cec149872021-09-26T00:30:02ZengMDPI AGJournal of Molecular Pathology2673-52612021-07-0122023324010.3390/jmp2030020Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist PerspectiveClaudio Bellevicine0Roberta Sgariglia1Mariantonia Nacchio2Caterina De Luca3Pasquale Pisapia4Francesco Pepe5Giancarlo Troncone6Department of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyMolecular testing has acquired a relevant role for diagnostic and prognostic stratification of indeterminate thyroid nodules. Besides the available commercial solutions marketed in the United States, various local testing strategies have been developed in the last decade. In this setting, the modern <i>interventional cytopathologist</i>, the physician who performs the both aspirate and the morphologic interpretation plays a key role in the correct handling of fine-needle aspiration (FNA) samples not only for microscopy but also for molecular techniques. This review summarizes experiences with local approaches to the molecular testing of thyroid FNA, highlighting the role of the modern interventional cytopathologist.https://www.mdpi.com/2673-5261/2/3/20interventional cytopathologistFNAthyroidmolecular techniquesmolecular pathologyNGS
collection DOAJ
language English
format Article
sources DOAJ
author Claudio Bellevicine
Roberta Sgariglia
Mariantonia Nacchio
Caterina De Luca
Pasquale Pisapia
Francesco Pepe
Giancarlo Troncone
spellingShingle Claudio Bellevicine
Roberta Sgariglia
Mariantonia Nacchio
Caterina De Luca
Pasquale Pisapia
Francesco Pepe
Giancarlo Troncone
Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective
Journal of Molecular Pathology
interventional cytopathologist
FNA
thyroid
molecular techniques
molecular pathology
NGS
author_facet Claudio Bellevicine
Roberta Sgariglia
Mariantonia Nacchio
Caterina De Luca
Pasquale Pisapia
Francesco Pepe
Giancarlo Troncone
author_sort Claudio Bellevicine
title Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective
title_short Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective
title_full Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective
title_fullStr Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective
title_full_unstemmed Molecular Testing of Thyroid Fine-Needle Aspiration: Local Issues and Solutions. An Interventional Cytopathologist Perspective
title_sort molecular testing of thyroid fine-needle aspiration: local issues and solutions. an interventional cytopathologist perspective
publisher MDPI AG
series Journal of Molecular Pathology
issn 2673-5261
publishDate 2021-07-01
description Molecular testing has acquired a relevant role for diagnostic and prognostic stratification of indeterminate thyroid nodules. Besides the available commercial solutions marketed in the United States, various local testing strategies have been developed in the last decade. In this setting, the modern <i>interventional cytopathologist</i>, the physician who performs the both aspirate and the morphologic interpretation plays a key role in the correct handling of fine-needle aspiration (FNA) samples not only for microscopy but also for molecular techniques. This review summarizes experiences with local approaches to the molecular testing of thyroid FNA, highlighting the role of the modern interventional cytopathologist.
topic interventional cytopathologist
FNA
thyroid
molecular techniques
molecular pathology
NGS
url https://www.mdpi.com/2673-5261/2/3/20
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AT robertasgariglia moleculartestingofthyroidfineneedleaspirationlocalissuesandsolutionsaninterventionalcytopathologistperspective
AT mariantonianacchio moleculartestingofthyroidfineneedleaspirationlocalissuesandsolutionsaninterventionalcytopathologistperspective
AT caterinadeluca moleculartestingofthyroidfineneedleaspirationlocalissuesandsolutionsaninterventionalcytopathologistperspective
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