Amelioration of Behavioral Impairments and Neuropathology by Antiepileptic Drug Topiramate in a Transgenic Alzheimer’s Disease Model Mice, APP/PS1

Amelioration of Behavioral Impairments and Neuropathology by Antiepileptic Drug Topiramate in a Transgenic Alzheimer’s Disease Model Mice, APP/PS1

Alzheimer’s disease (AD) is a neurodegenerative disease that is the main cause of dementia in the elderly. The aggregation of β-amyloid peptides is one of the characterizing pathological changes of AD. Topiramate is an antiepileptic drug, which in addition, is used in the treatmen...

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Bibliographic Details
Main Authors: Brice Ayissi Owona, Caroline Zug, Hermann J. Schluesener, Zhi-Yuan Zhang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
APP/PS1 transgenic mouse
topiramate
amyloidosis
Online Access:https://www.mdpi.com/1422-0067/20/12/3003

Internet

https://www.mdpi.com/1422-0067/20/12/3003

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