Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways
Melanoma is the deadliest form of skin cancer, and its incidence has continuously increased over the past 20 years. Therefore, the discovery of a novel targeted therapeutic strategy for melanoma is urgently needed. In our study, MTT-based cell proliferation assay, cell cycle, and apoptosis assays th...
Main Authors: | Qian Zhao, Hong-Ping Zhu, Xin Xie, Qing Mao, Yan-Qing Liu, Xiang-Hong He, Cheng Peng, Qing-Lin Jiang, Wei Huang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/5/1845 |
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