Molecular docking studies of selected medicinal drugs as dengue virus-2 protease inhibitors
Dengue is a potentially deadly disease with no effective drug. An in silico molecular docking was performed using Autodock 4.2.6 to investigate the molecular interactions between protease inhibitors, comprising antibiotic derivatives namely doxycycline (3), rolitetracycline (5) and a non-steroidal a...
Main Authors: | Rufaidah Othman (Author), Rozana Othman (Author), Aida Baharuddin (Author), Nagasundara Ramanan Ramakrishnan (Author), Noorsaadah Abd Rahman (Author), Rohana Yusof (Author), Saiful Anuar Karsani (Author) |
---|---|
Format: | Article |
Language: | English |
Published: |
Penerbit Universiti Kebangsaan Malaysia,
2017-10.
|
Online Access: | Get fulltext |
Similar Items
-
Inhibition of dengue NS2B-NS3 protease and viral replication in Vero cells by recombinant retrocyclin-1
by: Rothan Hussin A, et al.
Published: (2012-11-01) -
Protegrin-1 Inhibits Dengue NS2B-NS3 Serine Protease and Viral Replication in MK2 Cells
by: Hussin A. Rothan, et al.
Published: (2012-01-01) -
Comparative proteomics reveals that YK51, a 4-Hydroxypandurantin-A analogue, downregulates the expression of proteins associated with dengue virus infection
by: Wei-Lian Tan, et al.
Published: (2018-01-01) -
Design of New Competitive Dengue Ns2b/Ns3 Protease Inhibitors—A Computational Approach
by: Noorsaadah Abd. Rahman, et al.
Published: (2011-02-01) -
Thioguanine-based DENV-2 NS2B/NS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling.
by: Maywan Hariono, et al.
Published: (2019-01-01)