Malaysian nasal polyps: eosinophil or neutrophil-predominant

Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data...

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Main Authors: Syuhada O (Author), Shalini P (Author), Lim, WK (Author), Ammar A (Author), Suria Hayati Md Pauzi (Author), Aneeza Khairiyah Wan Hamizan (Author), Balwant Singh Gendeh (Author), Noraidah Masir (Author), Salina Husain (Author)
Format: Article
Language:English
Published: Fakulti Perubatan, UKM, 2016.
Online Access:Get fulltext
LEADER 01748 am a22002173u 4500
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042 |a dc 
100 1 0 |a Syuhada O,   |e author 
700 1 0 |a Shalini P,   |e author 
700 1 0 |a Lim, WK  |e author 
700 1 0 |a Ammar A,   |e author 
700 1 0 |a Suria Hayati Md Pauzi,   |e author 
700 1 0 |a Aneeza Khairiyah Wan Hamizan,   |e author 
700 1 0 |a Balwant Singh Gendeh,   |e author 
700 1 0 |a Noraidah Masir,   |e author 
700 1 0 |a Salina Husain,   |e author 
245 0 0 |a Malaysian nasal polyps: eosinophil or neutrophil-predominant 
260 |b Fakulti Perubatan, UKM,   |c 2016. 
856 |z Get fulltext  |u http://journalarticle.ukm.my/9788/1/8._Syuhada_et_al..pdf 
520 |a Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data was recorded. The histological slides were retrieved. The number of eosinophils and non-eosinophils were counted and average number of inflammatory cells for each high power field was calculated. Eosinophil-predominant was seen in 32.8% of patients and 67.2% was non-eosinophil-predominant. Phenotypes of NP significantly showed an association with ethnicity (x² = 8.322; p < 0.05). A total of 78.9% of Chinese nasal polyps showed non-eosinophil predominant, while Malay and Indian nasal polyps revealed 71.9% and 40.7% of non-eosinophilic phenotype, respectively. Our study showed that Malaysian population had a non-eosinophilic phenotype of nasal polyps. There was a significant association in Malaysian ethnicity with the highest percentage in Chinese population. 
546 |a en