Metabolomic analysis of Akt1-mediated muscle hypertrophy in models of diet-induced obesity and age-related fat accumulation
Akt1 is a serine/threonine kinase that promotes cell growth and survival. Previously, Akt1 activation in a double transgenic (DTG) mouse model fed a high-fat/high-sucrose (HF/HS) diet was found to promote type IIb muscle growth and to lead to a significant reduction in obesity. Here, we have used me...
Main Authors: | Cheng, Kian Kai (Author), Akasaki, Yuichi (Author), Lecommandeur, Emmanuell (Author), Lindsay, Ross T. (Author), Murfitt, Steven A. (Author), Walsh, Kenneth (Author), Griffin, Julian L. (Author) |
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Format: | Article |
Language: | English |
Published: |
American Chemical Society,
2014.
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Subjects: | |
Online Access: | Get fulltext |
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