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85094 |
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|a Zaini, Ahmad Syahmi
|e author
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|a Aris, Noor Aiysah
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|a Putra, Nicky Rahmana
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|a Abd. Hashib, Syafiza
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|a Kamaruddin, Mohd. Johari
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|a Idham, Zuhaili
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|a Che Yunus, Mohd. Azizi
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|a Comparison of charantin extract from Momordica charantia using modified supercritical carbon dioxide and soxhlet extraction method
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|b Penerbit UTM Press,
|c 2018.
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|z Get fulltext
|u http://eprints.utm.my/id/eprint/85094/1/MohdAziziCheYunus2018_ComparisonofCharantinExtractfromMomordica.pdf
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|a Charantin extract from Momordica charantia fruits for the anti-diabetic compound was proposed via Supercritical Fluid Extraction using carbon dioxide (SC-CO2) as a solvent. This method is a promising alternative technique to a conventional Soxhlet and shaking water bath extraction method. Experiments were conducted to analyze the charantin i) with and without a modifier (ethanol), ii) Soxhlet extraction with four types of solvent (distilled water, ethanol, dichloromethane, and petroleum ether) and iii) shaking water bath with distilled water as a solvent. A purification step was conducted post extraction to remove intrusive components such as chlorophylls and sugar from the analyte in order to quantify charantin extract using high-performance liquid chromatography (HPLC). The results show that in 2.5 hours SC-CO2 with ethanol as modifier gives highest charantin yield with 0.7817 mg charantin per gram sample. In contrast, shaking water bath gives the highest charantin yield for a conventional method with 0.712 mg charantin per gram sample during 6 hours of extraction. The result shows that by using SC-CO2 modified with ethanol can be a promising "green" extraction than a conventional method.
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|a en
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|a TP Chemical technology
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