Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
We used a collection of 708 prospectively collected autopsied brains to assess the methylation state of the brain's DNA in relation to Alzheimer's disease (AD). We found that the level of methylation at 71 of the 415,848 interrogated CpGs was significantly associated with the burden of AD...
Similar Items
-
Allosteric Effects of G-Protein Coupled Receptor Heteromerization: Relevance to Psychosis
by: Younkin, Jason W
Published: (2016) -
A genome-wide association study in mice reveals a role for Rhbdf2 in skeletal homeostasis
by: Roei Levy, et al.
Published: (2020-02-01) -
A genome-wide association study in mice reveals a role for Rhbdf2 in skeletal homeostasis
by: Roei Levy, et al.
Published: (2020-10-01) -
ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.
by: Diego Mastroeni, et al.
Published: (2017-01-01) -
Correction: ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.
by: Diego Mastroeni, et al.
Published: (2018-01-01)