Biomarkers and diagnostic tools for detection of Helicobacter pylori

Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world's population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economi...

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Bibliographic Details
Main Authors: Khalilpour, Akbar (Contributor), Kazemzadeh-Narbat, Mehdi (Contributor), Tamayol, Ali (Contributor), Oklu, Rahmi (Author), Khademhosseini, Ali (Author)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Khademhosseini, Alireza (Contributor)
Format: Article
Language:English
Published: Springer Berlin Heidelberg, 2016-09-21T19:23:42Z.
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Summary:Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world's population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.