De Novo Reconstruction of Adipose Tissue Transcriptomes Reveals Long Non-coding RNA Regulators of Brown Adipocyte Development

De Novo Reconstruction of Adipose Tissue Transcriptomes Reveals Long Non-coding RNA Regulators of Brown Adipocyte Development

Brown adipose tissue (BAT) protects against obesity by promoting energy expenditure via uncoupled respiration. To uncover BAT-specific long non-coding RNAs (lncRNAs), we used RNA-seq to reconstruct de novo transcriptomes of mouse brown, inguinal white, and epididymal white fat and identified ∼1,500...

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Bibliographic Details
Main Authors: Bai, Zhiqiang (Author), Xu, Dan (Author), Yuan, Bingbing (Author), Lo, Kinyui Alice (Author), Yoon, Myeong Jin (Author), Lim, Yen Ching (Author), Knoll, Marko (Author), Chen, Shuai (Author), Chen, Peng (Author), Sun, Lei (Author), Alvarez, Juan Rene (Contributor), Slavov, Nikolai G (Contributor), Lodish, Harvey F (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-12-13T15:00:06Z.
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