De Novo Reconstruction of Adipose Tissue Transcriptomes Reveals Long Non-coding RNA Regulators of Brown Adipocyte Development
Brown adipose tissue (BAT) protects against obesity by promoting energy expenditure via uncoupled respiration. To uncover BAT-specific long non-coding RNAs (lncRNAs), we used RNA-seq to reconstruct de novo transcriptomes of mouse brown, inguinal white, and epididymal white fat and identified ∼1,500...
Main Authors: | Bai, Zhiqiang (Author), Xu, Dan (Author), Yuan, Bingbing (Author), Lo, Kinyui Alice (Author), Yoon, Myeong Jin (Author), Lim, Yen Ching (Author), Knoll, Marko (Author), Chen, Shuai (Author), Chen, Peng (Author), Sun, Lei (Author), Alvarez, Juan Rene (Contributor), Slavov, Nikolai G (Contributor), Lodish, Harvey F (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2016-12-13T15:00:06Z.
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Subjects: | |
Online Access: | Get fulltext |
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