Crystal structure of a substrate-engaged SecY protein-translocation channel
Hydrophobic signal sequences target secretory polypeptides to a protein-conducting channel formed by a heterotrimeric membrane protein complex, the prokaryotic SecY or eukaryotic Sec61 complex. How signal sequences are recognized is poorly understood, particularly because they are diverse in sequenc...
Main Authors: | Li, Long (Author), Park, Eunyong (Author), Rapoport, Tom A. (Author), Ling, Jingjing (Contributor), Ingram, Jessica (Contributor), Ploegh, Hidde (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor) |
Format: | Article |
Language: | English |
Published: |
Springer Nature,
2017-03-07T16:15:19Z.
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Subjects: | |
Online Access: | Get fulltext |
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