Atomic structure of anthrax protective antigen pore elucidates toxin translocation
Anthrax toxin, comprising protective antigen, lethal factor, and oedema factor, is the major virulence factor of Bacillus anthracis, an agent that causes high mortality in humans and animals. Protective antigen forms oligomeric prepores that undergo conversion to membrane-spanning pores by endosomal...
Main Authors: | Jiang, Jiansen (Author), Pentelute, Bradley L. (Author), Zhou, Z. Hong (Author), Collier, Robert John (Contributor) |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2017-04-14T14:38:12Z.
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Subjects: | |
Online Access: | Get fulltext |
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