MenaINV dysregulates cortactin phosphorylation to promote invadopodium maturation
Invadopodia, actin-based protrusions of invasive carcinoma cells that focally activate extracellular matrix-degrading proteases, are essential for the migration and intravasation of tumor cells during dissemination from the primary tumor. We have previously shown that cortactin phosphorylation at ty...
Main Authors: | Weidmann, Maxwell D. (Author), Surve, Chinmay R. (Author), Eddy, Robert J. (Author), Chen, Xiaoming (Author), Sharma, Ved P. (Author), Condeelis, John S. (Author), Gertler, Frank (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor) |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2017-04-21T18:49:08Z.
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Subjects: | |
Online Access: | Get fulltext |
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