A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory

A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory

The SNARE-mediated vesicular transport pathway plays major roles in synaptic remodeling associated with formation of long-term memories, but the mechanisms that regulate this pathway during memory acquisition are not fully understood. Here we identify miRNAs that are up-regulated in the rodent hippo...

Full description

Bibliographic Details
Main Authors: Mathew, Rebecca S (Author), Tatarakis, Antonis (Author), Johnson-Venkatesh, Erin M (Author), Murphy, Elisabeth A (Author), Todd, Travis P (Author), Schepers, Scott T (Author), Siuti, Nertila (Author), Falls, William A (Author), Hammack, Sayamwong E (Author), Walsh, Christopher A (Author), Umemori, Hisashi (Author), Bouton, Mark E (Author), Moazed, Danesh (Author), Rudenko, Andrii (Contributor), Martorell, Anthony (Contributor), Tsai, Li-Huei (Contributor), Yang, Yawei (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd., 2017-05-02T13:46:10Z.
Subjects:
Article
Online Access:Get fulltext

Similar Items

Similar Items