Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Genetic variants affecting hematopoiesis can influence commonly measured blood cell traits. To identify factors that affect hematopoiesis, we performed association studies for blood cell traits in the population-based Estonian Biobank using high-coverage whole-genome sequencing (WGS) in 2,284 sample...

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Main Authors: Guo, Michael H. (Author), Nandakumar, Satish K. (Author), Ulirsch, Jacob C. (Author), Buenrostro, Jason D. (Author), Natarajan, Pradeep (Author), Salem, Rany M. (Author), Chiarle, Roberto (Author), Mitt, Mario (Author), Kals, Mart (Author), Pärn, Kalle (Author), Fischer, Krista (Author), Milani, Lili (Author), Mägi, Reedik (Author), Palta, Priit (Author), Metspalu, Andres (Author), Esko, Tõnu (Author), Zekavat, Seyedeh M. (Contributor), Gabriel, Stacey (Contributor), Lander, Eric Steven (Contributor), Kathiresan, Sekar (Contributor), Sankaran, Vijay G. (Contributor), Hirschhorn, Joel N. (Author)
Other Authors: Institute for Medical Engineering and Science (Contributor), Broad Institute of MIT and Harvard (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Hirschhorn, Joel N (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-05-11T19:42:39Z.
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