A requirement for filopodia extension toward Slit during Robo-mediated axon repulsion
Axons navigate long distances through complex 3D environments to interconnect the nervous system during development. Although the precise spatiotemporal effects of most axon guidance cues remain poorly characterized, a prevailing model posits that attractive guidance cues stimulate actin polymerizat...
Main Authors: | McConnell, Russell E. (Contributor), Van Veen, John (Contributor), Vidaki, Marina (Contributor), Kwiatkowski, Adam V (Contributor), Meyer, Aaron Samuel (Contributor), Gertler, Frank (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
Rockefeller University Press,
2017-05-31T13:14:51Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Slit-Dependent Endocytic Trafficking of the Robo Receptor Is Required for Son of Sevenless Recruitment and Midline Axon Repulsion.
by: Rebecca K Chance, et al.
Published: (2015-09-01) -
Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
by: Timothy A Evans, et al.
Published: (2015-07-01) -
Signaling from Within: Endocytic Trafficking of the Robo Receptor Is Required for Midline Axon Repulsion.
by: Frédéric Charron
Published: (2015-09-01) -
Coevolution of axon guidance molecule Slit and its receptor Robo.
by: Qi Yu, et al.
Published: (2014-01-01) -
Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2
by: Verity Johnson, et al.
Published: (2019-08-01)