Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers

Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers

The malaria liver stage is an attractive target for antimalarial development, and preclinical malaria models are essential for testing such candidates. Given ethical concerns and costs associated with non‐human primate models, humanized mouse models containing chimeric human livers offer a valuable...

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Bibliographic Details
Main Authors: Ng, Shengyong (Contributor), March, Sandra (Author), Galstian, Ani (Contributor), Gural, Nil (Contributor), Stevens, Kelly R. (Contributor), Mota, Maria M. (Author), Bhatia, Sangeeta N. (Author), March-Riera, Sandra (Contributor), Prado, Mariana (Contributor), Bhatia, Sangeeta N (Contributor)
Other Authors: Institute for Medical Engineering and Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Center for International Studies (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-06-20T18:28:06Z.
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