Parallel transmission pulse design with explicit control for the specific absorption rate in the presence of radiofrequency errors

• Main Authors: Schiavi, Emanuele (Author), Eryaman, Yigitcan (Author), Herraiz, Joaquin L. (Author), Gagoski, Borjan (Author), Guerin, Bastien (Author), Martin Fernandez, Adrian (Contributor), Adalsteinsson, Elfar (Contributor), Wald, Lawrence (Contributor)
• Other Authors: Institute for Medical Engineering and Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
• Format: Article
• Language: English
• Published: Wiley Blackwell, 2017-07-18T15:33:30Z.
• Subjects: Article
• Online Access: Get fulltext

Purpose A new framework for the design of parallel transmit (pTx) pulses is presented introducing constraints for local and global specific absorption rate (SAR) in the presence of errors in the radiofrequency (RF) transmit chain. Methods The first step is the design of a pTx RF pulse with explicit constraints for global and local SAR. Then, the worst possible SAR associated with that pulse due to RF transmission errors ("worst-case SAR") is calculated. Finally, this information is used to re-calculate the pulse with lower SAR constraints, iterating this procedure until its worst-case SAR is within safety limits. Results Analysis of an actual pTx RF transmit chain revealed amplitude errors as high as 8% (20%) and phase errors above 3° (15°) for spokes (spiral) pulses. Simulations show that using the proposed framework, pulses can be designed with controlled "worst-case SAR" in the presence of errors of this magnitude at minor cost of the excitation profile quality. Conclusion Our worst-case SAR-constrained pTx design strategy yields pulses with local and global SAR within the safety limits even in the presence of RF transmission errors. This strategy is a natural way to incorporate SAR safety factors in the design of pTx pulses.
National Institutes of Health (U.S.) (R01EB006847)