Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c
Cortico-basal ganglia circuits are critical for speech and language and are implicated in autism spectrum disorder, in which language function can be severely affected. We demonstrate that in the mouse striatum, the gene Foxp2 negatively interacts with the synapse suppressor gene Mef2c. We present c...
Main Authors: | Chen, Yi-Chuan (Author), Kuo, Hsiao-Ying (Author), Bornschein, Ulrich (Author), Takahashi, Hiroshi (Author), Chen, Shih-Yun (Author), Lu, Kuan-Ming (Author), Yang, Hao-Yu (Author), Chen, Gui-May (Author), Lin, Jing-Ruei (Author), Lee, Yi-Hsin (Author), Chou, Yun-Chia (Author), Cheng, Sin-Jhong (Author), Chien, Cheng-Ting (Author), Enard, Wolfgang (Author), Hevers, Wulf (Author), Pääbo, Svante (Author), Graybiel, Ann M (Contributor), Liu, Fu-Chin (Author) |
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Other Authors: | McGovern Institute for Brain Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
Springer Nature,
2017-11-14T18:59:15Z.
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Subjects: | |
Online Access: | Get fulltext |
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