Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c

Cortico-basal ganglia circuits are critical for speech and language and are implicated in autism spectrum disorder, in which language function can be severely affected. We demonstrate that in the mouse striatum, the gene Foxp2 negatively interacts with the synapse suppressor gene Mef2c. We present c...

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Bibliographic Details
Main Authors: Chen, Yi-Chuan (Author), Kuo, Hsiao-Ying (Author), Bornschein, Ulrich (Author), Takahashi, Hiroshi (Author), Chen, Shih-Yun (Author), Lu, Kuan-Ming (Author), Yang, Hao-Yu (Author), Chen, Gui-May (Author), Lin, Jing-Ruei (Author), Lee, Yi-Hsin (Author), Chou, Yun-Chia (Author), Cheng, Sin-Jhong (Author), Chien, Cheng-Ting (Author), Enard, Wolfgang (Author), Hevers, Wulf (Author), Pääbo, Svante (Author), Graybiel, Ann M (Contributor), Liu, Fu-Chin (Author)
Other Authors: McGovern Institute for Brain Research at MIT (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2017-11-14T18:59:15Z.
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