An Integrative Framework Reveals Signaling-to-Transcription Events in Toll-like Receptor Signaling
Building an integrated view of cellular responses to environmental cues remains a fundamental challenge due to the complexity of intracellular networks in mammalian cells. Here, we introduce an integrative biochemical and genetic framework to dissect signal transduction events using multiple data ty...
Main Authors: | Yosef, Nir (Author), Qiao, Jana (Author), Raychowdhury, Raktima (Author), Maritzen, Tanja (Author), Haucke, Volker (Author), Satoh, Takashi (Author), Akira, Shizuo (Author), Mertins, Philipp (Contributor), Przybylski, Dariusz (Contributor), Eisenhaure, Thomas (Contributor), Carr, Steven A (Contributor), Regev, Aviv (Contributor), Hacohen, Nir (Contributor), Chevrier, Nicolas (Contributor), Clauser, Karl R. (Author) |
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Other Authors: | Broad Institute of MIT and Harvard (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Clauser, Karl R (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2018-01-23T19:07:28Z.
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Subjects: | |
Online Access: | Get fulltext |
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