A Unified Continuous Flow Assembly-Line Synthesis of Highly Substituted Pyrazoles and Pyrazolines
A rapid and modular continuous flow synthesis of highly functionalized fluorinated pyrazoles and pyrazolines has been developed. Flowing fluorinated amines through sequential reactor coils mediates diazoalkane formation and [3+2] cycloaddition to generate more than 30 azoles in a telescoped fashion....
Main Authors: | Britton, Joshua (Contributor), Jamison, Timothy F (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry (Contributor), Jamison, Timothy F. (Contributor) |
Format: | Article |
Language: | English |
Published: |
Wiley Blackwell,
2018-04-04T15:51:44Z.
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Subjects: | |
Online Access: | Get fulltext |
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