A Unified Continuous Flow Assembly-Line Synthesis of Highly Substituted Pyrazoles and Pyrazolines

A rapid and modular continuous flow synthesis of highly functionalized fluorinated pyrazoles and pyrazolines has been developed. Flowing fluorinated amines through sequential reactor coils mediates diazoalkane formation and [3+2] cycloaddition to generate more than 30 azoles in a telescoped fashion....

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Bibliographic Details
Main Authors: Britton, Joshua (Contributor), Jamison, Timothy F (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor), Jamison, Timothy F. (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2018-04-04T15:51:44Z.
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