Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens

We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtu...

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Bibliographic Details
Main Authors: Husvogt, Lennart (Author), Vardeh, Hilde (Author), Sheykin, Yury (Author), Faulkner-Jones, Beverly E. (Author), Hornegger, Joachim (Author), Brooker, Jeff (Author), Cable, Alex (Author), Connolly, James L. (Author), Giacomelli, Michael (Contributor), Yoshitake, Tadayuki (Contributor), Cahill, Lucas Christopher (Contributor), Ahsen, Osman Oguz (Contributor), Fujimoto, James G (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: SPIE, 2018-04-17T13:54:26Z.
Subjects:
Online Access:Get fulltext
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100 1 0 |a Husvogt, Lennart  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science  |e contributor 
100 1 0 |a Giacomelli, Michael  |e contributor 
100 1 0 |a Yoshitake, Tadayuki  |e contributor 
100 1 0 |a Cahill, Lucas Christopher  |e contributor 
100 1 0 |a Ahsen, Osman Oguz  |e contributor 
100 1 0 |a Fujimoto, James G  |e contributor 
700 1 0 |a Vardeh, Hilde  |e author 
700 1 0 |a Sheykin, Yury  |e author 
700 1 0 |a Faulkner-Jones, Beverly E.  |e author 
700 1 0 |a Hornegger, Joachim  |e author 
700 1 0 |a Brooker, Jeff  |e author 
700 1 0 |a Cable, Alex  |e author 
700 1 0 |a Connolly, James L.  |e author 
700 1 0 |a Giacomelli, Michael  |e author 
700 1 0 |a Yoshitake, Tadayuki  |e author 
700 1 0 |a Cahill, Lucas Christopher  |e author 
700 1 0 |a Ahsen, Osman Oguz  |e author 
700 1 0 |a Fujimoto, James G  |e author 
245 0 0 |a Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens 
260 |b SPIE,   |c 2018-04-17T13:54:26Z. 
856 |z Get fulltext  |u http://hdl.handle.net/1721.1/114749 
520 |a We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting. 
546 |a en_US 
655 7 |a Article 
773 |t Multiphoton Microscopy in the Biomedical Sciences XVI