Palladium-Mediated Arylation of Lysine in Unprotected Peptides
A mild method for the arylation of lysine in an unprotected peptide is presented. In the presence of a preformed biarylphosphine-supported palladium(II)-aryl complex and a weak base, lysine amino groups underwent C−N bond formation at room temperature. The process generally exhibited high selectivit...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Wiley-Blackwell,
2018-05-02T18:50:17Z.
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| Subjects: | |
| Online Access: | Get fulltext |