Twenty-five years of mTOR: Uncovering the link from nutrients to growth
In my PNAS Inaugural Article, I describe the development of the mTOR field, starting with efforts to understand the mechanism of action of the drug rapamycin, which ∼25 y ago led to the discovery of the mTOR protein kinase. I focus on insights that we have contributed and on work that has been parti...
Main Author: | Sabatini, David (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
Proceedings of the National Academy of Sciences,
2018-06-15T14:22:37Z.
|
Subjects: | |
Online Access: | Get fulltext |
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