Normal aging induces A1-like astrocyte reactivity
The decline of cognitive function occurs with aging, but the mechanisms responsible are unknown. Astrocytes instruct the formation, maturation, and elimination of synapses, and impairment of these functions has been implicated in many diseases. These findings raise the question of whether astrocyte...
Main Authors: | Clarke, Laura E. (Author), Liddelow, Shane A. (Author), Chakraborty, Chandrani (Author), Münch, Alexandra E. (Author), Heiman, Myriam (Contributor), Barres, Ben A. (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor) |
Format: | Article |
Language: | English |
Published: |
Proceedings of the National Academy of Sciences,
2018-09-11T18:55:24Z.
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Subjects: | |
Online Access: | Get fulltext |
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