Cell contraction induces long-ranged stress stiffening in the extracellular matrix
Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains largely unknown how cells, in turn, affect the nonlinear mecha...
Main Authors: | Ronceray, Pierre (Author), Lenz, Martin (Author), Broedersz, Chase P. (Author), han, yulong (Contributor), Xu, Guoqiang (Contributor), Guo, Ming (Contributor), Malandrino, Andrea (Contributor), Kamm, Roger Dale (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
Proceedings of the National Academy of Sciences,
2018-12-13T20:54:11Z.
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Subjects: | |
Online Access: | Get fulltext |
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