3D-resolved targeting of photodynamic therapy using temporal focusing

3D-resolved targeting of photodynamic therapy using temporal focusing

A method for selectively inducing apoptosis in tumor nodules is presented, with close-to-cellular level resolution, using 3D-resolved widefield temporal focusing illumination. Treatment times on the order of seconds were achieved using Verteporfin as the photosensitizer, with doses of 30 μg ml-1and...

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Bibliographic Details
Main Authors: Klein, Oliver (Author), Evans, Conor L (Author), Rowlands, Christopher (Contributor), Wu, Jacqueline J (Contributor), Uzel, Sebastien GM (Contributor), So, Peter T. C. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2019-01-15T19:17:05Z.
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