Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e

ER-associated degradation (ERAD) is essential for protein quality control in the ER, not only when the ER is stressed, but also at steady state. We report a new layer of homeostatic control, in which ERAD activity itself is regulated posttranscriptionally and independently of the unfolded protein re...

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Bibliographic Details
Main Authors: Hagiwara, Masatoshi (Author), Ling, Jingjing (Author), Koenig, Paul-Albert (Author), Ploegh, Hidde L. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2019-06-20T15:28:45Z.
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