Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e
ER-associated degradation (ERAD) is essential for protein quality control in the ER, not only when the ER is stressed, but also at steady state. We report a new layer of homeostatic control, in which ERAD activity itself is regulated posttranscriptionally and independently of the unfolded protein re...
Main Authors: | Hagiwara, Masatoshi (Author), Ling, Jingjing (Author), Koenig, Paul-Albert (Author), Ploegh, Hidde L. (Author) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier BV,
2019-06-20T15:28:45Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
BAT3 Guides Misfolded Glycoproteins Out of the Endoplasmic Reticulum
by: Ploegh, Hidde, et al.
Published: (2012) -
BAT3 guides misfolded glycoproteins out of the endoplasmic reticulum.
by: Jasper H L Claessen, et al.
Published: (2011-01-01) -
Glycoprotein Quality Control and Endoplasmic Reticulum Stress
by: Qian Wang, et al.
Published: (2015-07-01) -
Studies on the quality control apparatus of glycoprotein folding in the endoplasmic reticulum
by: Pelletier, Marc-François.
Published: (2001) -
Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum
by: Ploegh, Hidde, et al.
Published: (2014)