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121523 |
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|a de Carlo, Talisa E.
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|a Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
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|a Massachusetts Institute of Technology. Research Laboratory of Electronics
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|a Adhi, Mehreen
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|a Lu, Chen David
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|a Duker, Jay S.
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|a Fujimoto, James G
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|a Waheed, Nadia K.
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|a Ultra-High Resolution Optical Coherence Tomography Imaging of Unilateral Drusen in a 31 Year Old Woman
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|b ClinMed International Library,
|c 2019-07-08T20:23:04Z.
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|z Get fulltext
|u https://hdl.handle.net/1721.1/121523
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|a We report a case of widespread unilateral drusen in a healthy 31 year old Caucasian woman using multi-modal imaging including ultra-high resolution optical coherence tomography (UHR-OCT). Dilated fundus exam showed multiple drusen-like lesions in the posterior pole without heme or fluid. Fundus auto fluorescence demonstrated hyperautofluorescent at the deposits. Fluorescein angiography revealed mild hyperfluorescence and staining of the lesions. Spectral-domain optical coherence tomography (SD-OCT) OS showed accumulations in the temporal macula at Bruch's membrane. UHR-OCT provided improved axial resolution compared to the standard 5 μm on the commercial SD-OCT and confirmed the presence of deposits in Bruch's membrane, consistent with drusen. The retinal layers were draped over the excrescences but did not show any disruption. Keywords: Drusen; Optical Coherence Tomography; Retinal Imaging; Retina
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|a National Institutes of Health (U.S.) (Grant R01-EY011289-29)
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|a National Institutes of Health (U.S.) (Grant R44-EY022864-02)
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|a National Institutes of Health (U.S.) (Grant R01-CA075289-17)
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|a Air Force Office of Scientific Research (Grant FA9550-10-1-0551)
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|a Air Force Office of Scientific Research (Grant FA9550-12-1-0499)
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|a en
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|a Article
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|t Clinical Medical Reviews and Case Reports
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