Synthetic biology devices as tools for metabolic engineering

Metabolic engineering focuses on controlling cellular metabolism and heterologous pathway flux to maximize the production of a product of interest. In recent years, various " devices" have begun to emerge from synthetic biology which could find widespread application in the field of metabo...

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Bibliographic Details
Main Authors: Shiue, Eric (Author), Prather, Kristala L (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2019-10-16T19:58:59Z.
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Online Access:Get fulltext
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100 1 0 |a Shiue, Eric  |e author 
100 1 0 |a Massachusetts Institute of Technology. Department of Chemical Engineering  |e contributor 
700 1 0 |a Prather, Kristala L  |e author 
245 0 0 |a Synthetic biology devices as tools for metabolic engineering 
260 |b Elsevier BV,   |c 2019-10-16T19:58:59Z. 
856 |z Get fulltext  |u https://hdl.handle.net/1721.1/122606 
520 |a Metabolic engineering focuses on controlling cellular metabolism and heterologous pathway flux to maximize the production of a product of interest. In recent years, various " devices" have begun to emerge from synthetic biology which could find widespread application in the field of metabolic engineering. In this review, we describe devices from synthetic biology and discuss the difficulties that may be encountered when using these devices as tools for metabolic engineering. Keywords: Synthetic biology devices; Metabolic engineering; Process integration; Large scale cultivation; Sensors; Scale-up 
546 |a en 
655 7 |a Article 
773 |t Biochemical Engineering Journal