CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data
Tiling screens that use CRISPR-Cas technologies provide a powerful approach for the mapping of regulatory elements to phenotypes of interest1-6. Here we present CRISPR screening uncharacterized region function (CRISPR-SURF), a deconvolution framework that can be used to identify functional regulator...
| Main Authors: | , , , , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Springer Science and Business Media LLC,
2020-05-21T19:12:31Z.
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| Subjects: | |
| Online Access: | Get fulltext |