A cysteine-based molecular code informs collagen C-propeptide assembly
Fundamental questions regarding collagen biosynthesis, especially with respect to the molecular origins of homotrimeric versus heterotrimeric assembly, remain unanswered. Here, we demonstrate that the presence or absence of a single cysteine in type-I collagen's C-propeptide domain is a key fac...
Main Authors: | DiChiara, Andrew Stephen (Author), Li, Rasia C. (Author), Suen, Patreece H. (Author), Hosseini, Azade S. (Author), Taylor, Rebecca J. (Author), Weickhardt, Alexander F. (Author), Malhotra, Diya (Author), Shoulders, Matthew D. (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry (Contributor), McGovern Institute for Brain Research at MIT (Contributor) |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC,
2020-05-28T17:31:58Z.
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Subjects: | |
Online Access: | Get fulltext |
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