Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis

Pyruvate Kinase Regulates the Pentose-Phosphate Pathway in Response to Hypoxia in Mycobacterium tuberculosis

In response to the stress of infection, Mycobacterium tuberculosis (Mtb) reprograms its metabolism to accommodate nutrient and energetic demands in a changing environment. Pyruvate kinase (PYK) is an essential glycolytic enzyme in the phosphoenolpyruvate-pyruvate-oxaloacetate node that is a central...

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Main Authors: Zhong, Wenhe (Author), Guo, Jingjing (Author), Cui, Liang (Author), Chionh, Yok Hian (Author), Li, Kuohan (Author), El Sahili, Abbas (Author), Cai, Qixu (Author), Yuan, Meng (Author), Michels, Paul A.M (Author), Fothergill-Gilmore, Linda A. (Author), Walkinshaw, Malcolm D. (Author), Mu, Yuguang (Author), Lescar, Julien (Author), Dedon, Peter C (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier BV, 2020-06-19T21:56:46Z.
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