Systematic analysis of the intersection of disease mutations with protein modifications

BACKGROUND: Perturbed posttranslational modification (PTM) landscapes commonly cause pathological phenotypes. The Cancer Genome Atlas (TCGA) project profiles thousands of tumors allowing the identification of spontaneous cancer-driving mutations, while Uniprot and dbSNP manage genetic disease-associ...

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Bibliographic Details
Main Authors: Simpson, Claire M. (Author), Zhang, Bin (Author), Hornbeck, Peter V (Author), Gnad, Florian (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: BioMed Central, 2020-08-13T13:45:58Z.
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