Hyperconjugative Antiaromaticity Activates 4 H -Pyrazoles as Inverse-Electron-Demand Diels-Alder Dienes
The Diels-Alder reactivity of 4,4-difluoro-3,5-diphenyl-4H-pyrazole was investigated experimentally and computationally with endo-bicyclo[6.1.0]non-4-yne. The computationally predicted rate enhancement from hyperconjugative antiaromaticity induced by fluorination of cyclopentadienes at the 5-positio...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society (ACS),
2020-11-20T18:37:43Z.
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| Subjects: | |
| Online Access: | Get fulltext |