Covariate-Adaptive Optimization in Online Clinical Trials

The decision of how to allocate subjects to treatment groups is of great importance in experimental clinical trials for novel investigational drugs, a multibillion-dollar industry. Statistical power, the ability of an experiment to detect a positive treatment effect when one exists, depends in part...

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Bibliographic Details
Main Authors: Bertsimas, Dimitris J (Author), Korolko, Nikita (Nikita E.) (Author), Weinstein, Alexander Michael (Author)
Other Authors: Sloan School of Management (Contributor)
Format: Article
Language:English
Published: Institute for Operations Research and the Management Sciences (INFORMS), 2021-02-18T15:24:43Z.
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