Covariate-Adaptive Optimization in Online Clinical Trials
The decision of how to allocate subjects to treatment groups is of great importance in experimental clinical trials for novel investigational drugs, a multibillion-dollar industry. Statistical power, the ability of an experiment to detect a positive treatment effect when one exists, depends in part...
Main Authors: | Bertsimas, Dimitris J (Author), Korolko, Nikita (Nikita E.) (Author), Weinstein, Alexander Michael (Author) |
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Other Authors: | Sloan School of Management (Contributor) |
Format: | Article |
Language: | English |
Published: |
Institute for Operations Research and the Management Sciences (INFORMS),
2021-02-18T15:24:43Z.
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Subjects: | |
Online Access: | Get fulltext |
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