Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD

Dysfunction of cortical GABAergic neurons leads to sensory hyper-reactivity in a Shank3 mouse model of ASD

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Hyper-reactivity to sensory input is a common and debilitating symptom in individuals with autism spectrum disorders (ASD), but the neural basis underlying sensory abnormality is not completely understood. Here we examined the neural representations of sensory perception in the neocortex of a Shank3...

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Main Authors: Chen, Qian (Author), Deister, Christopher A. (Author), Gao, Xian (Author), Guo, Baolin (Author), Lynn-Jones, Taylor (Author), Chen, Naiyan (Author), Wells, Michael F. (Author), Liu, Runpeng (Author), Goard, Michael J. (Author), Dimidschstein, Jordane (Author), Feng, Shijing (Author), Shi, Yiwu (Author), Liao, Weiping (Author), Lu, Zhonghua (Author), Fishell, Gord (Author), Moore, Christopher I. (Author), Feng, Guoping (Author)
Other Authors: McGovern Institute for Brain Research at MIT (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor)
Format: Article
Language:English
Published: Springer Science and Business Media LLC, 2022-03-14T18:14:56Z.
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