Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers

© 2016 Elsevier Inc. Generic spinal motor neuron identity is established by cooperative binding of programming transcription factors (TFs), Isl1 and Lhx3, to motor-neuron-specific enhancers. How expression of effector genes is maintained following downregulation of programming TFs in maturing neuron...

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Main Authors: Rhee, Ho Sung (Author), Closser, Michael (Author), Guo, Yuchun (Author), Bashkirova, Elizaveta V. (Author), Tan, G. Christopher (Author), Gifford, David K. (Author), Wichterle, Hynek (Author)
Format: Article
Language:English
Published: Elsevier BV, 2022-05-18T15:46:28Z.
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