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|a Ghotra, Anpreet
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|a Kosakowski, Heather L
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|a Takahashi, Atsushi
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|a Etzel, Robin
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|a May, Markus W
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|a Scholz, Alina
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|a Jansen, Andreas
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|a Wald, Lawrence L
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|a Kanwisher, Nancy
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|a Saxe, Rebecca
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|a Keil, Boris
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|a A size‐adaptive 32‐channel array coil for awake infant neuroimaging at 3 Tesla MRI
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|b Wiley,
|c 2021-12-01T17:08:49Z.
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|z Get fulltext
|u https://hdl.handle.net/1721.1/138273
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|a PURPOSE: Functional magnetic resonance imaging (fMRI) during infancy poses challenges due to practical, methodological, and analytical considerations. The aim of this study was to implement a hardware-related approach to increase subject compliance for fMRI involving awake infants. To accomplish this, we designed, constructed, and evaluated an adaptive 32-channel array coil. METHODS: To allow imaging with a close-fitting head array coil for infants aged 1-18 months, an adjustable head coil concept was developed. The coil setup facilitates a half-seated scanning position to improve the infant's overall scan compliance. Earmuff compartments are integrated directly into the coil housing to enable the usage of sound protection without losing a snug fit of the coil around the infant's head. The constructed array coil was evaluated from phantom data using bench-level metrics, signal-to-noise ratio (SNR) performances, and accelerated imaging capabilities for both in-plane and simultaneous multislice (SMS) reconstruction methodologies. Furthermore, preliminary fMRI data were acquired to evaluate the in vivo coil performance. RESULTS: Phantom data showed a 2.7-fold SNR increase on average when compared with a commercially available 32-channel head coil. At the center and periphery regions of the infant head phantom, the SNR gains were measured to be 1.25-fold and 3-fold, respectively. The infant coil further showed favorable encoding capabilities for undersampled k-space reconstruction methods and SMS techniques. CONCLUSIONS: An infant-friendly head coil array was developed to improve sensitivity, spatial resolution, accelerated encoding, motion insensitivity, and subject tolerance in pediatric MRI. The adaptive 32-channel array coil is well-suited for fMRI acquisitions in awake infants.
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|a en
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|a Article
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|t 10.1002/MRM.28791
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|t Magnetic Resonance in Medicine
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